Nutrition and Dementia: The MIND Trial by Dr. Martha Clare Morris

Nutrition and Dementia: The MIND Trial by Dr. Martha Clare Morris

Dr. Martha Clare Morris, Rush Alzheimer’s Disease Center, offers the keynote address for the 2017 Wisconsin Alzheimer’s Disease Research Center Fall Lecture – “The Science Behind Alzheimer’s Disease Prevention and Brain Health.” She details the research behind her MIND diet for healthy brain aging.


  1. Ben Nguyen on June 15, 2021 at 10:59 pm

    Regarding the chart at the 8m mark, surprised there is no distinction between the source of the saturated fat.. i.e. red-meat/tallow vs dairy/butter/ghee vs coconut/palm? I understand saturated fats raise cholesterol, but whole foods usually contain a mix of fats.. ex. butter is 1/3 monounsaturated fats, meat 1/2 monounsaturated, eggs are 2/3 unsaturated, etc.
    Regarding how the Gamma tocopherol form of Vitamin-E found in foods, is more beneficial than the Alpha tocopherol (presynaptic proteins) commonly found in supplements… Dr. Barrie Tan suggests that its Delta/Gamma tocoTRIENOLS that are protective (found in Achiote/Annatto paste). Interesting, in the early 90’s Joel Wallach was saying how they cure dementia-like symptoms in animals with high doses of vitamin-e!

    Aside from eating fish 1+/week, any thoughts on the VITAL study that suggests DHA/Omega-3 supplements, at least for CVD, doesn’t seem to help much?

    Probably a good idea to get one’s blood level tested for Folate (B9) / B12 / Zn / Mg… otherwise one might over-consume nuts. I like the part of strawberries for motor function, blue-berries for the cognitive benefits… my favorite is black-raspberries (not to be confused with blackberries)!

    BTW, forgot to mention, there was a good episode of the BrainWaves podcast "#135 Brain Food" that suggests the evidence for nutrition to slow AD isn’t very strong.. and that there’s some evidence for statins to help cognition/memory?!

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  3. Kenneth Moore on June 15, 2021 at 11:13 pm

    The study findings suggest that the MIND diet substantially slows cognitive decline with age. Replication of these findings in a dietary intervention trial would be required to verify its relevance to brain health.

  4. Paul Frank on June 15, 2021 at 11:19 pm

    Good video. Actually the isolation of alpha tocopherol was probably the biggest mistake in nutritional history. The following video describes this mistake in detail as well as why it failed as an antioxidant.

  5. Anjana Agarwal on June 15, 2021 at 11:28 pm

    just poised and phenomenal
    Good learning for me

  6. Kenneth Moore on June 15, 2021 at 11:28 pm

    evidence-based and realistic (finally)

    Recommendations that may slow cognitive decline
    • Regular physical activity, e.g., brisk walking for 30-45 minutes, 5-6 times per week
    • Regular mental stimulation, e.g., watching documentaries versus reality TV, reading magazines, learning new information about subjects that interest you
    • Mediterranean diet or similar diet shown to reduce vascular risk
    o Foods with benefit: nuts, oils, green leafy vegetables, whole grain, berries, tea, chocolate, fish
    o Avoid saturated fats (red meat and dairy) and trans fats (commercial foods and baked goods)
    • Maintaining connection with friends, church, and community activities
    • Volunteer time for your favorite charity
    • Stress management techniques, e.g., using a dialectical perspective
    • Limit intake of sweets and rapidly absorbed sugars
    • Realistic weight loss to reduce risk of diabetes mellitus and metabolic syndrome
    • Smoking cessation
    • Limit alcohol intake to 1 drink per day
    • Have your doctor check cholesterol and triglycerides, treat hypercholesterolemia
    • Have blood pressure checked regularly and treat hypertension if nondrug measures do not reduce systolic blood pressure below 150 mmHg
    • Get professional advice regarding treatment of depression symptoms—sadness, insomnia, inappropriate guilt feelings, low energy, poor concentration, loss of appetite, apathy, suicidal thoughts or plan
    • Sleep hygiene, 7-8 hours of restful sleep nightly
    • Get medical attention early for medical problems. Even mild problems like dehydration or severe constipation can cause a rapid decline in memory or thinking. If you have diabetes or another medical problem that is not well controlled by you and your family physician, consider consultation with a specialist
    • Avoid medications like Benadryl that can cause abrupt decompensation in patients with mild cognitive impairment

  7. Weather Moon on June 15, 2021 at 11:32 pm

    Seems I need to increase my strawberry consumption (not a fan)

  8. The Rich Solution on June 15, 2021 at 11:44 pm

    Thanks for talking on this subject so important to get the information out there…awareness!

  9. Weather Moon on June 15, 2021 at 11:45 pm

    Would those who have a genetic chance of Alzheimer’s also have a metabolic disorder that prohibits Vitamin E absorbtion?